Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Start telling love stories and chances are, you’ll find yourself telling tales of transgression. In this hour of To the Best of Our Knowledge, Joyce Carol Oates talks about the harm done by family secrets. P.D. James muses on why women are so good at crime fiction. A...Read more
Many Americans think the story of Cuba begins and ends with Fidel Castro. But the soul of the Cuban Revolution belonged to the charismatic, Romantic guerilla hero Ernesto “Che” Guevara. To the Best of Our Knowledge revisits the Sixties and counts the private costs of that era’s social gains. ...Read more
It seems everyone has something to say about motherhood. A lot of people have advice. Others just have... issues. In this hour of To The Best of Our Knowledge -- the tricky topic of motherhood. Linda Gray Sexton remembers her mother, the troubled poet Anne...Read more
Are you a knave? Scalawag? A varlet? Are you a scoundrel? Maybe you’re not but secretly you want to be. Being a scoundrel kind of has a ring to it. It’s romantic. Rebellious.Read more
Malcolm Gladwell knows how to succeed in show business without really trying -- write a story for The New Yorker about a psychiatrist who studies serial killers. Then a playwright will take some of the words from your article and use them in a Broadway play. Next time on To the Best of Our...Read more
Back in 1967, Noam Chomsky wrote a famous essay called "The Responsibility of Intellectuals." Chomsky was furious about what he called "the deceit and distortion surrounding the American invasion of Vietnam." And he urged intellectuals "to speak the truth and expose lies." So what is the...Read more
Who are you? White or black, Muslim or Christian, working class or wealthy? Most of us rotate through many different cultural identities, at work and at home. And sometimes, reconciling them is hard.Read more
There’s a powerful new voting bloc in America. They’re white, working class, and they live in places that have been left behind. We'll talk with "Hillbilly Elegy" author J.D. Vance, and country music star Brandy Clark joins us in the studio to play some music and talk about her hometown.Read more
Here’s the truth: the wild romance will probably end. Wedding vows, intimacy, heartache… they can have a long shelf-life. But those butterflies in your stomach? Wild libidinal longings? They tend to quiet over time.
So what happens after the romance ends? From passionate marriage, to ...Read more
Graphic novelist Neil Gaiman has a talent for creating strange and fantastic worlds. His “Sandman” comic books helped spawn the Goth movement, and with characters called Dream and Death, he created a new mythology. In this hour of To the Best of Our Knowledge, we’ll visit with Neil Gaiman at...Read more
It used to be that comics were just for kids. Today, we call them "graphic novels," and they're one of the fastest growing forms of American literature. In this hour of To the Best of Our Knowledge, how graphic art grew up...with Will Eisner's biographer, Jules Feiffer, Dennis Kitchen, and...Read more
If you think about it, every day we receive countless services from complete strangers — the newspaper delivered to your door, the trash picked up at the crack of dawn, the fresh fruit for sale at the supermarket. There's a whole army of invisible workers powering our economy who we rarely get...Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
Is there anything science won’t tackle? The latest question neuroscientists are taking on is, “What makes something beautiful?” We're checking in with the scientists, the philosophers and the artists in this hour.Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
It's hard to wrap your head around the future of the human brrain. Augmented intelligence, memory playback, downloadable skills - it's all coming. We explore the future of the mind, and hear how a brain injury can transform your life.Read more
Take a stroll through a natural history museum these days and you’ll not only see dinosaurs, you’ll smell them. Get a whiff of T-rex’s halitosis, his dinner leftovers, and, well, how should I put this – his droppings, too! In this hour of To the Best of Our Knowledge, museums that tickle your...Read more
Is the NSA wiretapping story really new? Sure, whistle blower Edward Snowden is all over the news. But people were talking about federal surveillance ten years before leaked documents about “Prism.” In this hour, we take a look at what we know about government surveillance and when we knew it...Read more
America is in trouble. The decline of the dollar, climate change and the ugly math of Social Security and national debt are just a handful of the challenges facing the next generation. And who's to blame for the current mess? Baby Boomers - according to a growing movement, pitting one generation...Read more
Two people, a house, a pitchfork, and a barn. It's hard to find a better-known American painting than Grant Wood's masterpiece "American Gothic." But just who are those grim people, and why do they have such a hold on the American psyche? Here's the history of an American classic. Also, a...Read more
Scientists have proven what pet owners already knew - cuddling with your dog or cat is good for you – and for your pet. In this hour of To the Best of Our Knowledge, keeping animals well, and how they return the favor. From gorilla conservation and eco-tourism to the dilemmas posed...Read more
Suppose neuroscientists map the billions of neural circuits in the human brain....are we any closer to cracking the great existential mysteries - like meaning,...Read more
Mary Ann Caws is an internationally respected scholar of surrealism. She has translated many of the movements major texts and is the editor of “Surrealism (Themes and Movements).” Caws talks with Anne Strainchamps about the history of the surrealist movement. Also, we hear actor Steve O’Connell...Read more