Could you get the same therapeutic benefits of a psychedelic drug without actually tripping? Neuroscientist David Olson wants to re-engineer psychedelic molecules to remove the trip. If successful, he might revolutionize the treatment of mental disorders.More
Intelligent. Optimistic. Curious.
Science and Technology
Psychedelic therapy has shown great promise for treating depression, but it's still unclear why exactly it works. Psychiatrist Charles Raison wants to know if it's the drug or the trip that makes psychedelics so potent. Is it biology or consciousness?More
The news about psychedelics tends to focus on clinical trials and lab research. But there’s a long tradition of underground guides working with plant medicines who refer to "unseen beings" and plants as "teachers." Psychologist Rachel Harris talked with many women elders in the psychedelic underground. She calls them "spiritual warriors."More
Honey Rose is part of the next generation of witches. They perform traditional magic on TikTok, do tarot readings via email, and seek to control social media algorithms with spells. Producer Angelo Bautista wanted to learn more.More
Novelist Siri Hustvedt knows how the creative process feels. Neuroscientist Heather Berlin knows what it looks like in the brain. Together with Steve, they explore the emerging science of creativity.More
Daniel Bergner felt frustrated and helpless back when one of his closest family members — his brother — was diagnosed as having bipolar disorder. So Bergner decided to report out other possibilities for his brother’s healing.More
Maia Szalavitz is an expert in addiction. She is also someone who has experienced it personally as a young woman. It was during that time that she came upon a concept that is only now changing how we think about recovery on a mass scale —harm reduction.
More
Sutton King wants to change the culture around psychedelic medicines by confronting historical wrongs and getting Indigenous people into key decision-making roles in the psychedelic industry. More
Pharmaceutical companies have a long history of hunting for medicinal drugs, often in Indigenous cultures. Historian Lucas Richert tells the story of how one company went bioprospecting for peyote.More
Tool-making? Agriculture? Language? French neuroscientist Stanislas Dehaene believes there’s an even more basic cognitive skill that gave humans an evolutionary jump start — geometry.More
Math superstar Jordan Ellenberg reveals the geometrical underpinnings of pretty much everything — from pandemics to voting districts to the 14th dimension. If geometry is indeed "the cilantro of math," Ellenberg could convert even the most die-hard hater to the joy of shapes.More
Our producer Charles Monroe-Kane has a passion for ravens. The raven has meaning for him from legend and art, to the point where he’s had one tattooed on his forearm.More
Stephen Alvarez — a National Geographic photographer and founder of the Ancient Art Archive — has spent years documenting ancient rock art around the world. He takes Steve Paulson on a long hike in the Cumberland Plateau, where they find an "unnamed cave" with 2,000-year old engravings.More
Geologist Marcia Bjornerud has a profound understanding of Earth's deep history. The author of "Timefulness," she says geologic literacy would give us a much healthier sense of time. More
In the years when psychedelic science had been shut down, Amanda Feilding helped jump-start research into altered states of mind. Today, she's in her 80s and remains active in psychedelic research with her Beckley Foundation.More
Neuroscientist Christof Koch has pioneered the scientific investigation of consciousness. Recently, he had a mind-blowing experience — both terrifying and ecstatic — with 5-MeO-DMT, also known as toad venom.More
For years, Robin Carhart-Harris dreamed of using brain scans to study people on LSD. He’s gone on to conduct pioneering research on psilocybin, and he’s formulated a theory of the "entropic brain" to explain what happens during psychedelic experiences.More
Physicist Don Gurnett has recorded what you might hear from inside a spacecraft, and it isn't just the sound of desolate silence.More