Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Once upon a time people believed the world was populated with terrible monsters and fabulous mythical beasts. They thought if they just searched long enough and hard enough, they'd find them. In this hour of To the Best of Our Knowledge, the mythical beasts of folktale and legend and the modern...Read more
The public sees a politician one way. A political cartoonist sees something else entirely. What makes a good political cartoon? We’ll get some answers from Steve Brodner, one of the most savage illustrators at work in the United States. It’s The New Toons in this hour of To the Best of Our...Read more
We explore music and memory in this hour -- Kurt Cobain's lasting impact 20 years after his death; insidious and infectious earworms; and the retro worldly music of Pink Martini.Read more
With the elections approaching, candidates and campaigns are working hard to get out the vote. But what would it take to get people politically involved all year round? This hour we explore a few ways, whether it's by using games to make the political process more fun, or mobilizing activists...Read more
TTBOOK staffers share some of our favorite interviews and shows produced by our favorite Canadian. Read more
Uncovering the real story in Iraq is getting harder. Western journalists have become targets, just like American soldiers. And reporters now take elaborate precautions to avoid being killed or kidnaped. In this hour of To the Best of Our Knowledge we'll talk about the hazards of war reporting...Read more
Where’s James Bond when you need him? You have to wonder about the spy business after the dubious information that was used to justify America’s war against Iraq. In this hour of To the Best of Our Knowledge, an argument for revealing all the secrets to the public. And, a look back at Anthony...Read more
In the film-going arena, one man towers above all others. His endurance, stamina and tolerance for popcorn are unparalleled. In this hour of To the Best of Our Knowledge, Kevin Murphy’s quest to see a movie a day. Every day. For a Year. Also, writer Michael Ondaatje (ahn-dot-chee) on the...Read more
Tucker Crowe is a reclusive musician. His devoted fans consider him to be the creator of the greatest breakup album ever recorded. But Tucker Crowe doesn't actually exist. He's a character in "Juliet, Naked"...the new novel from "New York Times" best-selling author, Nick Hornby. We'll talk to...Read more
Have you ever wondered why Homer’s “Iliad” is still so popular? Bestselling writer Thomas Cahill says it’s because it’s a real boy’s story. On this hour of To the Best of Our Knowledge, our enduring fascination with the Ancient Greeks. Also, an archaeologist who’s excavating the real Troy. ...Read more
Her novel “Bel Canto” was a hit so now novelist Ann Patchett is a star. But back when they were in college, it was her fellow student Lucy Grealy who got treated like a rock star. In this hour of To the Best of Our Knowledge, a look at uncommon friendships. Ann Patchett tells how her...Read more
Is religion dangerous? Sam Harris blames the violent verses in the Koran and the Bible for inciting religious conflict around the world. Renowned religious historian Karen Armstrong says the core message of the major religions is the Golden Rule. In this hour of To the Best of Our Knowledge,...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
A few years ago, the notion of the "quantified self" was the domain of a relatively small group of hackers, engineers, and computer enthusiasts. Now, under its many names—lifelogging, self-tracking, fitness monitoring—it's become one of the fastest growing segments of the technology...Read more
Red roses, chilled champagne, a candlelight dinner for two. Who cares?!?
This is the 21st century. We’ve got 30 million potential dates online. We’ve got every imaginable type of pornography at our fingertips. Odds are each of us could hook up with someone new tonight.
...Read more
Salman Rushdie's new novel is called "The Enchantress of Florence." It's a tale of two cities, consisting of stories tucked inside stories tucked inside stories...along the lines of Scheherazade's stories of "One Thousand and One Nights." In this hour of To the Best of Our Knowledge, Salman...Read more
In this hour of To the Best of Our Knowledge, Russia and China. They were the two Communist giants. Now each is carving out a new future. By most accounts, China is doing it better. It’s still an authoritarian state, but the economy if booming. And Russia? Well, it’s capitalism’s wild...Read more
To mark the Winter Solstice, we’ll honor the sacred origins our secular Christmas decorations and hear a solstice story from India. And to help you get through the long winter evenings, we’ll get some recommendations for your winter reading list. Solstice myths and stories and provocative new...Read more
Film-maker David Lynch has been "diving within" through the Transcendental Meditation technique for more than 30 years. Now Lynch has created a foundation that wants to help students discover their full creative potential through T.M. In this hour of To the Best of Our Knowledge, David Lynch...Read more
He’s been called the “Godfather of hip-hop.” He rose from selling drugs on the streets to running a Fortune 500 company. He founded Def Jam Records and produced acts like Run DMC, Public Enemy, and LL Cool J. Next time on To the Best of Our Knowledge, Russell Simmons and hip-hop. Also, the...Read more
Chris Ayres never wanted to cover the war. He was perfectly content reporting on celebrity gossip in L.A. But through a twist of fate, he found himself embedded with Marines in Iraq, living in a Humvee and waiting for his death at the hands of the Republican Guard. In this hour of To the Best...Read more
Being a kid has never been cooler. In fact, it’s SO cool, it’s not just for the twelve and under set anymore. These days more adults watch the Cartoon Network than CNN, Care Bears are making a comeback, and Scoobie-Doo underpants come in grown-up sizes. In this hour of To the Best of Our...Read more