Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
What would you do if you found yourself in the presence of murderous evil? Would you sell out to survive, or would you resist and try to hang onto your values? For how long? Maybe you reject the whole concept of evil. In this hour of To the Best of Our Knowledge we'll meet some people who aren't...Read more
John Brown was a terrorist, a man who led a raid in Kansas that butchered five unarmed men. He was also, arguably, of the few white people in 1850s America who was totally color blind. According to a new book he was "the man who killed slavery and sparked the Civil War." So, was John Brown a "...Read more
Before there was Wikipedia… Before there was Facebook and Twitter… there was Ward Cunningham. The computer programmer who invented the first wiki, back in 1995. Cunningham also did something even more radical – he didn’t patent his invention. He passed up billions of dollars of potential...Read more
Uncovering the real story in Iraq is getting harder. Western journalists have become targets, just like American soldiers. And reporters now take elaborate precautions to avoid being killed or kidnaped. In this hour of To the Best of Our Knowledge we'll talk about the hazards of war reporting...Read more
Where’s James Bond when you need him? You have to wonder about the spy business after the dubious information that was used to justify America’s war against Iraq. In this hour of To the Best of Our Knowledge, an argument for revealing all the secrets to the public. And, a look back at Anthony...Read more
In this hour of To the Best of Our Knowledge, a visit with former Israeli commando Uri Avnery, who went on to become an outspoken critic of Israeli policy. He's seen his office bombed. He's been beaten and once barely survived an assassination attempt. Today Avnery is calling for a separate...Read more
Born 200 years ago, Charles Darwin was a revolutionary figure, and yet polls show that more than half of all Americans still don't accept his theory of evolution. So, is Darwinian evolution compatible with faith in God? In this hour of To the Best of Our Knowledge, what Darwin himself thought...Read more
Remember what it was like to be a kid, playing outside with friends for hours at a time? Sure, it may just seem like fun and games, but it may also have been invaluable training for life as an adult.Read more
“Good fences make good neighbors." Robert Frost writes in Mending Wall. Is he right? Maybe homemade chocolate chip cookies or lending a lawnmower are more neighborly. I guess it depends on who your neighbors are.Read more
Alex Rider, Nancy Drew, The Cat in the Hat, and Harold and the Purple Crayon – for millions of children of all ages, they're some of the most imaginative and mysterious stories around. But as it turns out, the authors sometimes have their own, personal mysteries to share. In this hour of To the...Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
Cameron Sinclair has something to say to architects out there: design like you give a damn. The founder of Architects for Humanity says the houses and office buildings we build today will literally shape the world our children inherit. So give a damn. In this hour of To the Best of Our...Read more
A fashion model with prosthetic legs… a musician who can’t hear… a writer who can’t see. Instead of disabled, differently-abled, handicapped – why not better-abled?Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
Eighty per cent of Americans say they believe in heaven. But when they're asked to describe it, many are at a loss for words. Do they think that there's another universe in the sky or do they believe that heaven is something more abstract and metaphorical? We'll explore our enduring fascination...Read more
These days it seems we just can’t get enough of it. Over the past few years, luxury spending in the United States has been growing four times faster than overall spending. We’re spending more money on more products and services that we don’t really need – like Evian bottled water and Prada...Read more
What if our lives were like DVDs? What if we had alternative endings to look forward to, instead of death? We explore our lust for immortality. And we look at the many alternative endings that Ernest Hemingway wrote for his classic novel, "A Farewell to Arms."
As artists and scientists explore the edges of our senses, what we touch, taste, see, smell, and hear is changing.
In this hour we hear from a psychiatrist who’s using touch to help people recover from trauma, investigate a mysterious sensory experience that gives some people euphoric...Read more
Investigative journalist Seymour Hersh made his name when he broke the story of the My Lai Massacre. Looking back you have to wonder: why did Lt. William Calley tell Hersh he’d killed hundreds of Vietnamese civilians? On this hour of To the Best of Our Knowledge Hersh says “because I asked him...Read more
Siberia is the name for a place we tend to think of as a metaphor as much as a destination on the map. Writer Ian Frazier indulged what he calls his dread Russia love with travels through Siberia, tracing the path of prisoners on their way to lonely exile and through mosquito-ridden swamps at...Read more
Crime may not pay but writing crime fiction does. Just ask the Swedish writer, Henning Mankell. Or those who write "Tartan Noir"...Scottish detective fiction. In this hour of To the Best of Our Knowledge, we'll explore Northern Europe's fictional crime wave. Also, Roger Ebert on film noir.Read more
Does anyone still hitchhike? Cult film director John Waters does. At the age of 66, he hitchhiked 2,800 miles, from Baltimore to San Francisco. He tells us about the people who picked him up, along with some who didn't. And did the America Interstate System pave the way...Read more
With the emergence of barefoot running, the sport suddenly is red hot again. But barefoot or not, are human bodies really born to run? We'll check in on the science or runner's high this hour, and try to unlock the secrets of the Kenyans - the fastest people on earth. Also, Olympic medalist...Read more