Neuroscientists have made remarkable discoveries about the brain, but so far, no one's come close to cracking the biggest mystery of all - the connection between the...Read more
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Episode Archives
 After one of the ugliest and most divisive presidential races in history -- can America heal? Weeks of vitriolic campaign rhetoric have taken a toll on friends and families. A majority of voters are disgusted with politics and don’t believe the next president will be able to unite the...Read more
Kashmir has been called the most beautiful place on earth. Today, it’s the melting point for a bitter dispute between India and Pakistan. It’s a situation that’s been called more dangerous than the Cuban missile crisis. In this hour of To the Best of Our Knowledge, an Indian writer mourns the...Read more
For decades, men have written about their first sexual experiences, but there’s almost no literature like that for women. In this hour of To the Best of Our Knowledge, memoirist Mary Karr reflects on her first kiss and other rites of passage for girls. Also, Jonathan Kozol describes...Read more
Imagine the world as we know it, only without us. In this hour of To the Best of Our Knowledge, a writer imagines a world reinventing itself without human beings. He sees the New York subway system returning to its watery origins. The re-absorption of carbon into the earth, and endangered...Read more
Charles Monroe-Kane grew up hearing voices in his head. For years he tried to drown them out with potentially lethal quantities of hard drugs and alcohol. Lithium saved his life but coming clean about his past hasn't been easy. How do you admit, as a public radio producer, that for years you had...Read more
Once upon a time people believed the world was populated with terrible monsters and fabulous mythical beasts. They thought if they just searched long enough and hard enough, they'd find them. In this hour of To the Best of Our Knowledge, the mythical beasts of folktale and legend and the modern...Read more
Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
The public sees a politician one way. A political cartoonist sees something else entirely. What makes a good political cartoon? We’ll get some answers from Steve Brodner, one of the most savage illustrators at work in the United States. It’s The New Toons in this hour of To the Best of Our...Read more
We explore music and memory in this hour -- Kurt Cobain's lasting impact 20 years after his death; insidious and infectious earworms; and the retro worldly music of Pink Martini.Read more
Uncovering the real story in Iraq is getting harder. Western journalists have become targets, just like American soldiers. And reporters now take elaborate precautions to avoid being killed or kidnaped. In this hour of To the Best of Our Knowledge we'll talk about the hazards of war reporting...Read more
Who's calling your shots? Who's in charge of your thinking, your perceptions? Maybe it's simple. Your mind is the boss, then your brain runs your body. Everything's fine. Until it's not and you find yourself confronting depression or autism or a head injury that leaves you with brain damage....Read more
With the elections approaching, candidates and campaigns are working hard to get out the vote. But what would it take to get people politically involved all year round? This hour we explore a few ways, whether it's by using games to make the political process more fun, or mobilizing activists...Read more
Where’s James Bond when you need him? You have to wonder about the spy business after the dubious information that was used to justify America’s war against Iraq. In this hour of To the Best of Our Knowledge, an argument for revealing all the secrets to the public. And, a look back at Anthony...Read more
You know the earth is round, the sky is up, and your dog loves you. But HOW do you know those things? This week, how we form opinions – the psychology and brain chemistry behind our beliefs.Read more
Remember the good old days? No? Well that's either because you haven't lived them yet, or you need to check the note you left on the bedside table. In this hour of To the Best of Our Knowledge, we're looking at age and memory with a Nobel Prize winner searching through the mechanics of the brain...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
When we’ve had enough of reality, we often seek escape in a movie.  But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
A few years ago, the notion of the "quantified self" was the domain of a relatively small group of hackers, engineers, and computer enthusiasts. Now, under its many names—lifelogging, self-tracking, fitness monitoring—it's become one of the fastest growing segments of the technology...Read more
Red roses, chilled champagne, a candlelight dinner for two. Who cares?!?
This is the 21st century. We’ve got 30 million potential dates online. We’ve got every imaginable type of pornography at our fingertips. Odds are each of us could hook up with someone new tonight.
...Read more
Salman Rushdie's new novel is called "The Enchantress of Florence." It's a tale of two cities, consisting of stories tucked inside stories tucked inside stories...along the lines of Scheherazade's stories of "One Thousand and One Nights." In this hour of To the Best of Our Knowledge, Salman...Read more