Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
John Brown was a terrorist, a man who led a raid in Kansas that butchered five unarmed men. He was also, arguably, of the few white people in 1850s America who was totally color blind. According to a new book he was "the man who killed slavery and sparked the Civil War." So, was John Brown a "...Read more
We explore music and memory in this hour -- Kurt Cobain's lasting impact 20 years after his death; insidious and infectious earworms; and the retro worldly music of Pink Martini.Read more
With the elections approaching, candidates and campaigns are working hard to get out the vote. But what would it take to get people politically involved all year round? This hour we explore a few ways, whether it's by using games to make the political process more fun, or mobilizing activists...Read more
Of all the days in the life of Nelson Mandela - the days in jail, awaiting sentence and his election in 94 - one day stood out as the most nerve-wracking. The day of the Rugby World Cup in 1995 - South Africa versus New Zealand. But it was much more than a sports match. It was the chance to...Read more
You know the earth is round, the sky is up, and your dog loves you. But HOW do you know those things? This week, how we form opinions – the psychology and brain chemistry behind our beliefs.Read more
Nicola Griffith wanted to fight back. A lesbian activist well-versed in the martial arts, Griffith knew she had the moves. But when her friend was attacked in a bar, she couldn't bring herself to hurt her attacker. In this hour of To the Best of Our Knowledge, the deadly, deep-minded lesbian...Read more
One day, an IRS auditor named Harold Crick wakes up to discover a voice in his head – a female voice narrating his life. That's the premise of the film, "Stranger Than Fiction." In this hour of To the Best of Our Knowledge, we'll meet the man who wrote the screenplay. Also, the story of Orson...Read more
Have you ever heard of Dan Rice? Probably not. But if you were alive around the middle of the nineteenth century chances are you would know his name. That’s when Dan Rice made his mark in “the show business.” In this hour of To the Best of Our Knowledge, the life and times of Dan Rice. And...Read more
Reading a good book may be the most fun you can have sitting down. Books can be a hobby or a passion, an interest or an obsession. In this hour of To the Best of Our Knowledge, tales from book world. A former bookseller takes us to Hay on Wye - the Welsh town that’s well on its way to...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
With shows in Milan, Paris and New York, it's fashion month across the Western World, and people are turning their eyes to runways. But does fashion really matter? Truth is, the garment industry is worth trillions of dollars, and employs millions of people. In this hour, we take a look at the...Read more
Want to learn a second or third language? You don’t have to slave away in a French seminar – it only takes a minute or two to pick up “ob.” Next time on tob-oo thob-ah bob-est ob-of ob-our knob-ow-lob-edge. Or should I say To the Best of Our Knowledge, word games, and secret...Read more
You know those end of the year lists? Best books, movies, music and so on? This hour, To the Best of Our Knowledge shares the best interviews from 2015. Plus a booklist or two.Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
Red roses, chilled champagne, a candlelight dinner for two. Who cares?!?
This is the 21st century. We’ve got 30 million potential dates online. We’ve got every imaginable type of pornography at our fingertips. Odds are each of us could hook up with someone new tonight.
...Read more
TTBOOK staffers share some of our favorite interviews and shows produced by our favorite Canadian. Read more
Everyone knows what comic books are about, right? But it's not all about people in long underwear hitting each other. This hour on To the Best of Our Knowledge, heroes, anti-heroes, and regular folks strutting their stuff in black and white.Read more
Seven hundred million people get their music from the Internet. More than 10 million people own iPods. Does this mean that compact discs and record companies are going the way of the gramophone and eight-track tapes? In this hour of To the Best of Our Knowledge, we'll look at this digital...Read more
It's not quite the Manhattan that we're familiar with. "The New York Times" is available in a "War-Free Edition" and there are rumors of an escaped tiger on the prowl in the Upper East Side. This is the setting of Jonathan Lethem's critically-acclaimed new novel, "Chronic City." On this To the...Read more
Toby Young thought he had it made. He had a prestigious job at Vanity Fair magazine, a press pass that got him in everywhere, and a suave British accent to boot. He was poised to take Manhattan. Then everything went wrong. In this hour of To the Best of Our Knowledge, flops, failures and...Read more
Suppose you drop a family photograph on the subway, is it still yours? Not if Brian Dunn finds it. He collects lost photos and makes them his own. I’m Jim Fleming. Next time on To the Best of Our Knowledge “Who owns what?” If there are copyrights are there copy “...Read more
Most movie stars will do anything to stay in the limelight. But Debra Winger didn’t care. Six years ago, she walked out of Hollywood. She even taped her retirement card above her mirror so she’d see it every day. Next time on To the Best of Our Knowledge, Debra Winger talks about the...Read more
One of the top-selling songs last year was by rapper Kanye West. But it wasn’t hardcore hip-hop, it was a gospel song called “Jesus Walks.” In this hour of To the Best of Our Knowledge, the rebirth of Gospel Music. We’ll look at where gospel came from and where it’s going. And, we’ll feel...Read more