Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Malcolm Gladwell knows how to succeed in show business without really trying -- write a story for The New Yorker about a psychiatrist who studies serial killers. Then a playwright will take some of the words from your article and use them in a Broadway play. Next time on To the Best of Our...Read more
Whether black from a bottomless cup or as a Frappuccino mocha skim latte, it’s our culture’s elixir, coffee. In this hour of To the Best of Our Knowledge, java, joe, or a cup of mud. Most of us drink it everyday, but few of us know the effects it has on the world’s economy, or even...Read more
David Rothenburg is a philosopher and a jazz clarinetist, who also loves birds. So one day he sat down in the National Aviary in Pittsburgh and started playing music. Lo and behold, a white-crested laughing thrush started singing with him, riffing on the tunes he played. Since then Rothenburg...Read more
Poet Nick Lantz has a darkly satirical take on American culture. Lately, he’s been thinking about political spin and how politicians speak. In this interview—the third in our series ...Read more
What would a secular society really look like? We take an unconventional look at religion, the fiction it inspires, and reflect on why William James' classic book on mysticism, "The Varieties of Religious Experience," still matters.Read more
What are the great country music singles? Patsy Cline’s “Crazy,” probably. George Jones’ “slobbing tearjerker,” “He Stopped Loving Her Today.” What about the Rolling Stones’ “Honky Tonk Women”? and Otis Redding’s “(Sittin’ On) the Dock of the Bay? According to the book “Heartaches by the...Read more
Ever dream of finding buried treasure? In this hour of To the Best of Our Knowledge, real-life treasure hunters like the two small-time prospectors who risked their lives in the Canadian tundra, and found one of the world’s biggest diamond mines. Also, hunting for dinosaur bones in the Gobi...Read more
What’s the best way to get someone to talk? NPR’s Terry Gross has done more interviewers than just about anyone else in public radio. But she prefers to talk to them long distance, with no eye contact. In this hour of To the Best of Our Knowledge, Terry Gross on the art of the interview.Read more
Is there anything science won’t tackle? The latest question neuroscientists are taking on is, “What makes something beautiful?” We're checking in with the scientists, the philosophers and the artists in this hour.Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
Take a stroll through a natural history museum these days and you’ll not only see dinosaurs, you’ll smell them. Get a whiff of T-rex’s halitosis, his dinner leftovers, and, well, how should I put this – his droppings, too! In this hour of To the Best of Our Knowledge, museums that tickle your...Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
"History is a gallery of pictures in which there are few originals and many copies." -- Alexis de TocquevilleRead more
Fifty Years ago James Watson and Francis Crick made history when they cracked the code for DNA. Watson was only 24 years old, and by no means the smartest scientist around. So why do some scientists make great discoveries? In this hour of To the Best of Our Knowledge, James Watson talks about...Read more
Everyone in your Facebook feed is falling for fake news–sharing it even when there's no way it can be true. They keep falling for it. But not you, right? You’re smart, well-educated. You can tell the difference. Or can you?Read more
Nerds are an easy target for humor in movies and on TV... with their thick black glasses, hopelessly out-of-fashion clothes, and over-enunciated diction. But there's a dark side to nerds. In this hour of To the Best of Our Knowledge, we'll find out how the nerd stereotype is harming our children...Read more
Everybody needs a little help, and some of us need a lot. In this hour of To the Best of Our Knowledge, we’ll meet some helpers - and they’re not all human. We’ll visit a stable where they do equine assisted therapy, and we’ll hear from a writer who’s a volunteer fireman in his small hometown...Read more
Do you ever have a right to kill? What about Israeli agents who assassinate Hamas leaders? Or suicide bombers who blow up their enemies? Do the ends justify the means? William Vollman has written a three-thousand page treatise on the morality of violence. In this hour of To the Best of Our...Read more
When he was 10-years-old, Brian Raftery realized he couldn't sing. Despite his lack of vocal prowess, Raftery is obsessed with karaoke. He's traveled around the world to trace karaoke's evolution from a cult fad to a multimillion-dollar industry. In this hour, we'll explore the world of karaoke...Read more
She's a little bit country. She's a little bit rock and roll. Carlene Carter grew up surrounded by music. She's the daughter of June Carter and the stepdaughter of Johnny Cash. And Carlene followed in their footsteps, with a few twists and turns along the way. In this hour of the Peabody Award-...Read more
Magic is an art, a philosophy, and a way of seeing the world. In this hour, we learn magic tricks from a stage magician, travel to India's last magician's colony, explore shamanic magic, and talk with magical novelists Erin Morgenstern (Night Circus) and Deborah Harkness (...Read more
How far would you go for something to eat? Paris? Mom’s house? The drive-through at Mickey D’s? I bet you wouldn’t swim thousands of miles, from Mexico to the Arctic, just to scarf up mud from the bottom of the ocean. Whales do, and they’ve been doing it every year for eons. In this hour...Read more
We explore the frontiers of brain science, from the neurobiology of emotions to recent discoveries about autism. Renowned neuroscientists Richard Davidson and V.S. Ramachandran reveal new insights into the brain, and we'll hear the story of one marriage saved by a diagnosis of Asperger Syndrome...Read more