Scientists are launching one of the most audacious projects ever conceived: a detailed map of the human brain, neuron by neron, synapse by synapse. For some scientists...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Spiderman had a pretty good summer last year, but J.K. Rowling wasn’t worried. When the sixth Harry Potter book came out, children trampled the web-slinger in their rush to bookstores and libraries. Which makes perfect sense to author and Arthurian scholar Jane Yolen. She says it’s all about...Read more
The legendary movie mogul Samuel Goldwyn once said, you should never predict anything, especially the future. But it’s human nature to go to extremes for a sneak peak of what lies around the corner. In this hour of To the Best of Our Knowledge, an astrophysicist sheds some light on...Read more
Lynne Truss created a sensation in Britain with a book whose title is a punch line: it’s a punctuation joke that says a panda is a black and white mammal and it “Eats, Shoots and Leaves.” Rules for punctuation and a good life, in this hour of To the Best of Our Knowledge.Read more
American citizens worry about suicide bombers on airplanes, but intelligence analysts say the real threat today is in cyberspace. Cyber attacks on American companies and military installations are on the rise. Could terrorist hackers take down America's power grid? Or financial networks. In...Read more
When Meg Gaines was diagnosed with terminal cancer, her doctor told her to go home and think about the quality, not the quantity, of her days. Instead she grabbed him by the bow-tie and said “I don’t think you understand. I intend to live.” Today Meg Gaines is helping other cancer patients...Read more
Outsiders used to be the outcasts, misfits, and under-employed. Today, they're indie, alternative and ahead of their time. Outsiders are thriving and they're changing the way we think about what is mainstream and what is alternative. You might even say that outsiders are the new insiders.Read more
Boots on the Ground: Stories from the War in Iraq
Part Four
President Obama says our combat mission in Iraq will end by August 31, 2010. This leaves many unanswered questions. What was our mission in Iraq? Did we succeed? What will...Read more
Linus has his security blanket. Renowned neurologist Oliver Sacks had the Periodic Table of the Elements. In this hour of To the Best of Our Knowledge, My Chemical Life. Oliver Sacks remembers a childhood steeped in chemistry. Also, Primo Levi survives Auschwitz, through chemistry. And,...Read more
According to a "New York Times" poll he's the third most famous person in Japan, right behind Hirohito and Bruce Lee. But the truth is he's not even a person, he's a giant green, radioactive lizard named Godzilla. In this hour of To the Best of Our Knowledge we'll explore the history of...Read more
Do you have a tattoo? One in five American adults do. It seems there are tattoo parlors everywhere. What’s most popular? Quotes from great works of literature. "So it goes."Read more
In case it’s not obvious: we LOVE books on TTBOOK. But we’re also incredibly picky about which books we choose for interviews.Read more
Classical musicians don't come with better pedigrees than violinist Anne Akiko Meyers. She's been wowing audiences since she was four, performs all over the world and has commissioned many new works. In this hour of To the Best of Our Knowledge, Meyers talks about why she chose to record popular...Read more
A car accident at twenty-one left John Callahan paralyzed. He’s become a very successful cartoonist -- poking fun at disabilities and the idiosyncrasies of life. His work has been described as “rude, shocking, tasteless, and depraved” – by his fans. Next time on To...Read more
It’s Oscar season and Hollywood is once again celebrating the best films of the year. It would seem that we're a nation obsessed with movies. As a country, we spend billions of dollars to watch them every year, and celebrate them with a variety of awards ceremonies. But what separates a...Read more
Here’s the bad news. You can get the thing you most want - a BMW, the winning lottery ticket, and you still won’t be any happier. The good news? You can survive the most devastating catastrophes and you’ll be back on your feet in less time than you think. Next time on To the Best of Our...Read more
Adventure writer Ann Jones recalls crossing Africa from Tangier to Cape Town in search of one special tribe. They’re guided by the “feminine” principles of compromise, tolerance and peace. Also, Tony Horwitz sets sail in the wake of Captain Cooke. We’ll hear about a Frenchman who never went...Read more
Sinatra swings it, Miles Davis jazzes it up, and Billy Holiday croons it from the heart. Next time on To the Best of Our Knowledge, the biography of a great American love song. In our second annual Valentine’s Day Show the Rogers and Hart hit “My Funny Valentine.” And our listeners share true...Read more
Nearly 2500 years ago, Socrates celebrated the pursuit of wisdom, and famously said “the unexamined life is not worth living.” But does rigorous self examination actually lead to a happy or fulfilled life? It didn’t seem to work some of history’s most famous philosophers, including...Read more
Boots on the Ground: Stories from the War in Iraq
Part One
Iraq. April 6, 2004. This day marked the Marines' heaviest fighting since Vietnam and was the start of the Iraqi insurgency. By the end of the day more than 40 Marines and...Read more
There are people in the world who love books – and there are people who would kill for books. In this hour of To the Best of Our Knowledge, the pleasures and perils of book collecting. We’ll go on the road with veteran book buyers Lawrence and Nancy Goldstone. And, we’ll meet...Read more
For centuries Western travelers have felt the pull of exotic places. Tibet has always held a special fascination. In this hour of To the Best of Our Knowledge, is the Western romance with Tibet grounded in reality, or based on some notion of Shangri-La? Also a look at Bruce...Read more
How do you win friends and influence people if you're an immigrant from Leningrad who's bullied at school? You write your way to friendship. That's what Gary Shteyngart did. We meet him in this hour as we explore creative writing. Also, the connection between alcohol and creativity. And how...Read more
We’re off to the scene of the crime. Need a lawyer? Maybe you should find an evidence broker. He’s the guy you go to see when you’ve been accused of a crime and you need witnesses to prove you didn’t do it. At least that’s how it worked in the 18th century. Novelist David Liss talks about...Read more