Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
It's the sesquicentennial of the Civil War -- it's been 150 years since that epic war began. Americans will commemorate and remember it from different points of view. In this hour of To the Best of Our Knowledge, Remembering the Civil War. We'll talk about soldiers' experiences on the...Read more
If grocery shopping isn’t your thing, here’s a new way to put food on the table: try sticking your arm under a rock until a big ol’ catfish clamps onto to you. In this hour of To the Best of Our Knowledge, noodling for catfish and other southern pastimes. Also, Texas singer Steve Earle’s...Read more
It's been more than four decades since the Civil Rights movement ended racial segregation in America. Yet few would say African-Americans are now fully integrated – or assimilated. In this hour of To the Best of Our Knowledge, African American writers talk about race, and how black history –...Read more
We explore music and memory in this hour -- Kurt Cobain's lasting impact 20 years after his death; insidious and infectious earworms; and the retro worldly music of Pink Martini.Read more
With the elections approaching, candidates and campaigns are working hard to get out the vote. But what would it take to get people politically involved all year round? This hour we explore a few ways, whether it's by using games to make the political process more fun, or mobilizing activists...Read more
Creativity is a little like obscenity: You know it when you see it, but you can't exactly define it....unless you're a neuroscientist. In labs around the...Read more
Computers permeate our lives. They scan our groceries. They entertain us. They keep us safe. But, can they write a poem? In this hour of To the Best of Our Knowledge, will your desktop be the next Bard? And, the life of the original rock n’ roll rebel: the 19th century French poet Arthur...Read more
Her novel “Bel Canto” was a hit so now novelist Ann Patchett is a star. But back when they were in college, it was her fellow student Lucy Grealy who got treated like a rock star. In this hour of To the Best of Our Knowledge, a look at uncommon friendships. Ann Patchett tells how her...Read more
In the film-going arena, one man towers above all others. His endurance, stamina and tolerance for popcorn are unparalleled. In this hour of To the Best of Our Knowledge, Kevin Murphy’s quest to see a movie a day. Every day. For a Year. Also, writer Michael Ondaatje (ahn-dot-chee) on the...Read more
Tucker Crowe is a reclusive musician. His devoted fans consider him to be the creator of the greatest breakup album ever recorded. But Tucker Crowe doesn't actually exist. He's a character in "Juliet, Naked"...the new novel from "New York Times" best-selling author, Nick Hornby. We'll talk to...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
In the recent election, the Tea Party emerged as a major force in American politics. It's a striking story, when a few years before, the "New York Times" was speculating about the demise of the Republican party. So, why the game change, after Barack Obama won the White House on a surge of...Read more
Everybody needs a little help, and some of us need a lot. In this hour of To the Best of Our Knowledge, we’ll meet some helpers - and they’re not all human. We’ll visit a stable where they do equine assisted therapy, and we’ll hear from a writer who’s a volunteer fireman in his small hometown...Read more
Everybody gets excited about whatever's new, but what about what's really, really old? In this hour of To the Best of Our Knowledge we commemorate geologic time. We'll meet the scientists who found the oldest object on Earth - a three point four billion year old zircon! And the Jazz...Read more
When he was 10-years-old, Brian Raftery realized he couldn't sing. Despite his lack of vocal prowess, Raftery is obsessed with karaoke. He's traveled around the world to trace karaoke's evolution from a cult fad to a multimillion-dollar industry. In this hour, we'll explore the world of karaoke...Read more
Think you know your history? Then, of course, you remember Martin Luther King's famous "If I Had A Hammer" speech. And you know that Joan of Arc was Noah's wife...and she was at rest on Mount Arafat. And you don't need me to remind you that Marie Curie won the Noel Prize for inventing the...Read more
Are you an experimental innovator who works by trial and error and is most creative later in life, like Cezanne? Or are you a conceptual young genius like Picasso? We'll explore a theory that those are the two life cycles of artistic creativity.Read more
Al Green is often referred to as the minister of L-O-V-E. You know, a couple of candles, a back-rub, and Al Green on the stereo. In 1976, Al Green put all that behind him and became a real minister – the Reverend Al Green of the Full Gospel Tabernacle Church in Memphis, Tennessee. But now he's...Read more
When the Taliban took control of Kabul, many Afghans destroyed their books and TV sets. Belquis Ahmadi’s family left the country when women lost their rights. Today, Ahmadi lives in exile, campaigning for women to play a major role in a new Afghan government. Her story in this...Read more
America is in trouble. The decline of the dollar, climate change and the ugly math of Social Security and national debt are just a handful of the challenges facing the next generation. And who's to blame for the current mess? Baby Boomers - according to a growing movement, pitting one generation...Read more
Scientists have proven what pet owners already knew - cuddling with your dog or cat is good for you – and for your pet. In this hour of To the Best of Our Knowledge, keeping animals well, and how they return the favor. From gorilla conservation and eco-tourism to the dilemmas posed...Read more