Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Nicola Griffith wanted to fight back. A lesbian activist well-versed in the martial arts, Griffith knew she had the moves. But when her friend was attacked in a bar, she couldn't bring herself to hurt her attacker. In this hour of To the Best of Our Knowledge, the deadly, deep-minded lesbian...Read more
Plato argued that poets would be banished from the ideal republic. He said poets are only good for promoting petty emotions, such as anger and lust and love. In this hour of To the Best of Our Knowledge, poetry. We'll talk with four-time Slam Poet champion Patricia Smith about how powerful words...Read more
One day, an IRS auditor named Harold Crick wakes up to discover a voice in his head – a female voice narrating his life. That's the premise of the film, "Stranger Than Fiction." In this hour of To the Best of Our Knowledge, we'll meet the man who wrote the screenplay. Also, the story of Orson...Read more
Grim news from Africa is easy to find, but there are good things happening there too. The creator of the Number 1 Ladies’ Detective Agency wants you to know all about them. He calls himself a Utopian writer. In this hour of To the Best of Our Knowledge, we’ll visit the real Botswana with...Read more
In the film-going arena, one man towers above all others. His endurance, stamina and tolerance for popcorn are unparalleled. In this hour of To the Best of Our Knowledge, Kevin Murphy’s quest to see a movie a day. Every day. For a Year. Also, writer Michael Ondaatje (ahn-dot-chee) on the...Read more
Wouldn't it be great if we could predict the future? We could invest wisely, prepare for social change, and have next season's fashionable footwear.
But in our accelerated world, it seems increasingly difficult to figure out what the next big thing will be. In this hour, are trends a...Read more
Tucker Crowe is a reclusive musician. His devoted fans consider him to be the creator of the greatest breakup album ever recorded. But Tucker Crowe doesn't actually exist. He's a character in "Juliet, Naked"...the new novel from "New York Times" best-selling author, Nick Hornby. We'll talk to...Read more
"Everyone is on the Internet but they're not all talking with each other. There are groups upon groups out there, but they don't talk to one another. So while the Internet brings everyone into a share space, it does not necessarily bring them together." -- David LynchRead more
Remember the good old days? No? Well that's either because you haven't lived them yet, or you need to check the note you left on the bedside table. In this hour of To the Best of Our Knowledge, we're looking at age and memory with a Nobel Prize winner searching through the mechanics of the brain...Read more
You know the earth is round, the sky is up, and your dog loves you. But HOW do you know those things? This week, how we form opinions – the psychology and brain chemistry behind our beliefs.Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
Who would have guessed that number two on the Best Seller List this summer would be an intellectual thriller starring four brainy Princeton seniors and a 15th century manuscript written in code? In this hour of To the Best of Our Knowledge, meet the authors of “The Rule of Four.” Lost and...Read more
Chaotic headlines out of Washington, ice melting in Antarctica, world temps rising and global conflict on the rise… it could be worse. It could be Ragnarok. Writer Neil Gaiman retells the ancient Norse myth of the Twilight of the Gods and apocalyptic end of the world in his stunning new...Read more
It's not quite the Manhattan that we're familiar with. "The New York Times" is available in a "War-Free Edition" and there are rumors of an escaped tiger on the prowl in the Upper East Side. This is the setting of Jonathan Lethem's critically-acclaimed new novel, "Chronic City." On this To the...Read more