Scientists are launching one of the most audacious projects ever conceived: a detailed map of the human brain, neuron by neron, synapse by synapse. For some scientists...Read more
Intelligent. Optimistic. Curious.
Episode Archives
How do we know what's real? Can science tell us, or is there an unseen reality we'll never understand? We explore the borderlands of knowledge and reflect on some remarkable episodes in the history of science - Nobel laureates who investigated ghosts and a pioneer of quantum physics...Read more
John Cheever was sometimes called the "Chekov of the Suburbs." Cheever's characters often find themselves struggling with issues of conformity and class in American suburbia. Much like their creator himself. We'll explore the life and work of John Cheever with his biographer, Blake Bailey. Also...Read more
Are humans really unique? Not as much as we think, says renowned primatologist Frans de Waal. So what do our ape cousins - chimps & bonobos - think and feel? Also, the remarkable story of a feral child who lived with monkeys.
Spiderman had a pretty good summer last year, but J.K. Rowling wasn’t worried. When the sixth Harry Potter book came out, children trampled the web-slinger in their rush to bookstores and libraries. Which makes perfect sense to author and Arthurian scholar Jane Yolen. She says it’s all about...Read more
Outsiders used to be the outcasts, misfits, and under-employed. Today, they're indie, alternative and ahead of their time. Outsiders are thriving and they're changing the way we think about what is mainstream and what is alternative. You might even say that outsiders are the new insiders.Read more
Pragmatic.Problem-solving. And non-partisan -- Mayors just might be the next best hope for democracy.Read more
Future Perfect: Dreamers, Schemers & Visionaries
Part One
Imagine a poor child in Uruguay. Now imagine giving that young girl a hundred-dollar laptop computer. Imagine the educational opportunities that this laptop will provide...Read more
Shuttered businesses line the familiar streets of producer Charles Monroe-Kane’s hometown in the Rust Belt in northeastern Ohio. The steel mill where his father worked is shut down, locked behind chains. Opioid abuse is...Read more
Ten years after the end of apartheid, what’s left to document the struggle? For the filmmakers of the documentary “Amandla,” there’s music. In this hour of To the Best of Our Knowledge, the songs that faced down death, despair and terror on the road to equality in South Africa. Also, the...Read more
Do you have a tattoo? One in five American adults do. It seems there are tattoo parlors everywhere. What’s most popular? Quotes from great works of literature. "So it goes."Read more
What do you do if you're a struggling artist in search of recognition? Well, if you're Lynn Hershman Leeson, you write reviews of your work under pseudonyms and get them published in local newspapers. In this hour of To the Best of Our Knowledge, we'll find out how Hershman Leeson uses her art...Read more
Ahh, nature! It’s always such fun to watch on television. Let someone else stalk grizzlies and wrestle Amazonian snakes – real nature is hard work. But it doesn’t have to be. In this hour of To the Best of Our Knowledge we invite you to step out of your front door into the natural world. You...Read more
They’re the bad boys of the numerical system. You never know when one is going to crop up, or why. Mathematicians have agonized over their mysteries for years, some predicting a mystical order where only chaos appears. In this hour of To the Best of Our Knowledge, the world of prime numbers...Read more
Celebrate Halloween with this spooky hour full of ghost stories from our wonderful listeners, and real-life tales of the paranormal. Haunted houses, near-death experiences, and spectral raccoons... so many ways to be un-dead.Read more
Science and the Search for Meaning: Five Questions, Part One: What is Life?
Scientists can now explain virtually every stage of the evolutionary process. But there’s a basic question that still mystifies even the best scientists: How did life first begin on Earth...Read more
Classical musicians don't come with better pedigrees than violinist Anne Akiko Meyers. She's been wowing audiences since she was four, performs all over the world and has commissioned many new works. In this hour of To the Best of Our Knowledge, Meyers talks about why she chose to record popular...Read more
Are you deadline driven? Most focused, most productive as “zero hour” approaches? Well, what about the ultimate end, the true end of the time frame.
Deadline, indeed.
How does knowing that you’re going to die affect your life? In this hour we’re minding mortality.Read more
American flags are everywhere. U.S. soldiers are once again heroes. And some people say it’s downright unpatriotic to criticize the president or the war against terrorism. In this hour of To the Best of Our Knowledge, the new meaning of patriotism and the crackdown on dissent....Read more
Any day now, the United States will welcome the three hundred millionth American. He or she may be a new born baby, or someone who comes across the border – legally or illegally. In this hour of To the Best of Our Knowledge, we’ll look at America’s changing demographics, and consider the price...Read more
Jonathan Kaplan is a field doctor who travels to war zones around the world. He treats people who’ve been shot or maimed. Many of his patients die on the operating table. In this hour of To the Best of Our Knowledge what war looks like from the inside. Also singer/songwriter Steve Earle...Read more
American citizens worry about suicide bombers on airplanes, but intelligence analysts say the real threat today is in cyberspace. Cyber attacks on American companies and military installations are on the rise. Could terrorist hackers take down America's power grid? Or financial networks. In...Read more
Was Henry David Thoreau a failure? Hardly. Today, he's considered one of America's great writers. But his mentor, Ralph Waldo Emerson, called him the worst kind of failure: a dreamer. At Thoreau's funeral, Emerson said Thoreau was born for greatness, but he lacked ambition. He was nor more than...Read more
When Meg Gaines was diagnosed with terminal cancer, her doctor told her to go home and think about the quality, not the quantity, of her days. Instead she grabbed him by the bow-tie and said “I don’t think you understand. I intend to live.” Today Meg Gaines is helping other cancer patients...Read more