Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Imagine living your whole life in excruciating pain, 24/7, and actually choosing to go without any pain medication. Next time on To the Best of Our Knowledge, one man’s permanent pain. And is a teenager slashing her arms with a razor a cry for help or an ancient ritual of sacred pain? Also,...Read more
Have you ever heard of Dan Rice? Probably not. But if you were alive around the middle of the nineteenth century chances are you would know his name. That’s when Dan Rice made his mark in “the show business.” In this hour of To the Best of Our Knowledge, the life and times of Dan Rice. And...Read more
With shows in Milan, Paris and New York, it's fashion month across the Western World, and people are turning their eyes to runways. But does fashion really matter? Truth is, the garment industry is worth trillions of dollars, and employs millions of people. In this hour, we take a look at the...Read more
Imagine the world as we know it, only without us. In this hour of To the Best of Our Knowledge, a writer imagines a world reinventing itself without human beings. He sees the New York subway system returning to its watery origins. The re-absorption of carbon into the earth, and endangered...Read more
Charles Monroe-Kane grew up hearing voices in his head. For years he tried to drown them out with potentially lethal quantities of hard drugs and alcohol. Lithium saved his life but coming clean about his past hasn't been easy. How do you admit, as a public radio producer, that for years you had...Read more
Woody Allen is an Academy Award-winning film-maker and screenwriter, but he's notoriously media-shy. In this hour of To the Best of Our Knowledge, Eric Lax on talking to Woody Allen over 36 years. Also, we'll explore how independent screenplays work.Read more
Elephants mourning their dead. Chimpanzees dying of grief. And the everyday joy of a dog at play. Biologist Marc Bekoff says the evidence is all around us, if we learn how to see it. In this hour of To the Best of Our Knowledge, the case for animal emotions. And we’ll spend some time with a...Read more
In the early 1950's two-year-old Jacqueline Henley in New Orleans became darker. After the neighbors complained, her aunt turned her over to New Orleans authorities. A black couple wanted to adopt Jacqueline but -- she had the word “white” stamped on her birth certificate. Next time on To...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
Plato argued that poets would be banished from the ideal republic. He said poets are only good for promoting petty emotions, such as anger and lust and love. In this hour of To the Best of Our Knowledge, poetry. We'll talk with four-time Slam Poet champion Patricia Smith about how powerful words...Read more
The past is nebulous - a place no one can go. When we try to get our bearings there, we often find more than one truth. In this hour of To the Best of Our Knowledge, we’ll go back to Vietnam with Senator Bob Kerrey. And, one woman pieces together her past in war-torn Liberia. Also, paying...Read more
Suppose you drop a family photograph on the subway, is it still yours? Not if Brian Dunn finds it. He collects lost photos and makes them his own. I’m Jim Fleming. Next time on To the Best of Our Knowledge “Who owns what?” If there are copyrights are there copy “...Read more
You know the earth is round, the sky is up, and your dog loves you. But HOW do you know those things? This week, how we form opinions – the psychology and brain chemistry behind our beliefs.Read more
Anne D. LeClaire was walking along the beach on Nantucket Sound when she heard a voice. The voice said, "Sit in silence." LeClaire turned to look but there was no one there. Anne D. LeClaire talks about this experience seventeen years ago and how it inspired her to remain silent for two days...Read more
The Mississippi River is an American icon. It's a body of water that’s been shaped as much by cultural processes as by environmental ones. From the state lines it draws to its role in literature and the arts, it’s a river that flows deep in the American psyche.
This episode is about the...Read more
The Meaning of Life
Part Four
Pete Best should have been famous beyond his wildest dreams. He had Ringo's job just months before the Beatles' "Love Me Do" became a smash hit. But he got tossed out of the band and ended up working...Read more
From Soup to Nuts:
Part Two
This may be the century when Americans forget how to cook. We're just too busy. Take-out's too easy. And, who needs to cook when you can buy ready-made...Read more
Who would have guessed that number two on the Best Seller List this summer would be an intellectual thriller starring four brainy Princeton seniors and a 15th century manuscript written in code? In this hour of To the Best of Our Knowledge, meet the authors of “The Rule of Four.” Lost and...Read more
This hour we combine two seemingly unlikely things: food and death. But when you think about it food and death really do go hand-in-hand. From the Last Meal to the new phenomenon of Death Dinners. Read more
Chaotic headlines out of Washington, ice melting in Antarctica, world temps rising and global conflict on the rise… it could be worse. It could be Ragnarok. Writer Neil Gaiman retells the ancient Norse myth of the Twilight of the Gods and apocalyptic end of the world in his stunning new...Read more
Christopher Hogwood was not your ordinary household pet. For one thing, he weighed 700 pounds. And he loved to drink beer. Christopher was a very large pig with a heart of gold. In this hour of To the Best of Our Knowledge, the story of how Christopher Hogwood became the best-loved pig in...Read more