Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
The collapse of the twin towers gave birth to a strange new world. It was a city of fire and dust, rubble crunching under foot and eerie underground rivers. William Langewiesche was the only journalist with unrestricted access to Ground Zero. What he found there was startling, natural, and...Read more
Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
David Rothenburg is a philosopher and a jazz clarinetist, who also loves birds. So one day he sat down in the National Aviary in Pittsburgh and started playing music. Lo and behold, a white-crested laughing thrush started singing with him, riffing on the tunes he played. Since then Rothenburg...Read more
It seems everyone has something to say about motherhood. A lot of people have advice. Others just have... issues. In this hour of To The Best of Our Knowledge -- the tricky topic of motherhood. Linda Gray Sexton remembers her mother, the troubled poet Anne...Read more
Poet Nick Lantz has a darkly satirical take on American culture. Lately, he’s been thinking about political spin and how politicians speak. In this interview—the third in our series ...Read more
What’s the best way to get someone to talk? NPR’s Terry Gross has done more interviewers than just about anyone else in public radio. But she prefers to talk to them long distance, with no eye contact. In this hour of To the Best of Our Knowledge, Terry Gross on the art of the interview.Read more
Malcolm Gladwell knows how to succeed in show business without really trying -- write a story for The New Yorker about a psychiatrist who studies serial killers. Then a playwright will take some of the words from your article and use them in a Broadway play. Next time on To the Best of Our...Read more
There’s a powerful new voting bloc in America. They’re white, working class, and they live in places that have been left behind. We'll talk with "Hillbilly Elegy" author J.D. Vance, and country music star Brandy Clark joins us in the studio to play some music and talk about her hometown.Read more
Graphic novelist Neil Gaiman has a talent for creating strange and fantastic worlds. His “Sandman” comic books helped spawn the Goth movement, and with characters called Dream and Death, he created a new mythology. In this hour of To the Best of Our Knowledge, we’ll visit with Neil Gaiman at...Read more
She's a little bit country. She's a little bit rock and roll. Carlene Carter grew up surrounded by music. She's the daughter of June Carter and the stepdaughter of Johnny Cash. And Carlene followed in their footsteps, with a few twists and turns along the way. In this hour of the Peabody Award-...Read more
Back in 1967, Noam Chomsky wrote a famous essay called "The Responsibility of Intellectuals." Chomsky was furious about what he called "the deceit and distortion surrounding the American invasion of Vietnam." And he urged intellectuals "to speak the truth and expose lies." So what is the...Read more
Who are you? White or black, Muslim or Christian, working class or wealthy? Most of us rotate through many different cultural identities, at work and at home. And sometimes, reconciling them is hard.Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
It turns out that television may not be quite the "boob tube" and "the idiot box" that we thought it was. It seems that watching TV can actually make you smarter... by posing new cognitive challenges for your brain to solve. In this hour of To the Best of Our Knowledge, we'll explore the...Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
David Graeber was an iconoclastic anthropologist and influential radical thinker, one who popularized the rallying cry "We are the 99%." He died on Sept. 2 in Venice, Italy at age 59. Read more
Is there anything science won’t tackle? The latest question neuroscientists are taking on is, “What makes something beautiful?” We're checking in with the scientists, the philosophers and the artists in this hour.Read more
Fifty Years ago James Watson and Francis Crick made history when they cracked the code for DNA. Watson was only 24 years old, and by no means the smartest scientist around. So why do some scientists make great discoveries? In this hour of To the Best of Our Knowledge, James Watson talks about...Read more
Everybody needs a little help, and some of us need a lot. In this hour of To the Best of Our Knowledge, we’ll meet some helpers - and they’re not all human. We’ll visit a stable where they do equine assisted therapy, and we’ll hear from a writer who’s a volunteer fireman in his small hometown...Read more
Take a stroll through a natural history museum these days and you’ll not only see dinosaurs, you’ll smell them. Get a whiff of T-rex’s halitosis, his dinner leftovers, and, well, how should I put this – his droppings, too! In this hour of To the Best of Our Knowledge, museums that tickle your...Read more
Everyone in your Facebook feed is falling for fake news–sharing it even when there's no way it can be true. They keep falling for it. But not you, right? You’re smart, well-educated. You can tell the difference. Or can you?Read more
When he was 10-years-old, Brian Raftery realized he couldn't sing. Despite his lack of vocal prowess, Raftery is obsessed with karaoke. He's traveled around the world to trace karaoke's evolution from a cult fad to a multimillion-dollar industry. In this hour, we'll explore the world of karaoke...Read more
America is in trouble. The decline of the dollar, climate change and the ugly math of Social Security and national debt are just a handful of the challenges facing the next generation. And who's to blame for the current mess? Baby Boomers - according to a growing movement, pitting one generation...Read more