Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Intelligent. Optimistic. Curious.
Episode Archives
David Rothenburg is a philosopher and a jazz clarinetist, who also loves birds. So one day he sat down in the National Aviary in Pittsburgh and started playing music. Lo and behold, a white-crested laughing thrush started singing with him, riffing on the tunes he played. Since then Rothenburg...Read more
Poet Nick Lantz has a darkly satirical take on American culture. Lately, he’s been thinking about political spin and how politicians speak. In this interview—the third in our series ...Read more
It seems everyone has something to say about motherhood. A lot of people have advice. Others just have... issues. In this hour of To The Best of Our Knowledge -- the tricky topic of motherhood. Linda Gray Sexton remembers her mother, the troubled poet Anne...Read more
Calling Lynne Cox a swimmer is like calling Mohammed Ali a tough guy. At age fourteen, she swam to Catalina Island from mainland California. At eighteen she swam between the islands of New Zealand. Years later, with miles of hard swims behind her, she turned her eye to the unthinkable - the...Read more
Two people, a house, a pitchfork, and a barn. It's hard to find a better-known American painting than Grant Wood's masterpiece "American Gothic." But just who are those grim people, and why do they have such a hold on the American psyche? Here's the history of an American classic. Also, a...Read more
Malcolm Gladwell knows how to succeed in show business without really trying -- write a story for The New Yorker about a psychiatrist who studies serial killers. Then a playwright will take some of the words from your article and use them in a Broadway play. Next time on To the Best of Our...Read more
It used to be that comics were just for kids. Today, we call them "graphic novels," and they're one of the fastest growing forms of American literature. In this hour of To the Best of Our Knowledge, how graphic art grew up...with Will Eisner's biographer, Jules Feiffer, Dennis Kitchen, and...Read more
We explore the frontiers of brain science, from the neurobiology of emotions to recent discoveries about autism. Renowned neuroscientists Richard Davidson and V.S. Ramachandran reveal new insights into the brain, and we'll hear the story of one marriage saved by a diagnosis of Asperger Syndrome...Read more
If you think about it, every day we receive countless services from complete strangers — the newspaper delivered to your door, the trash picked up at the crack of dawn, the fresh fruit for sale at the supermarket. There's a whole army of invisible workers powering our economy who we rarely get...Read more
Who are you?
A man? A woman?
Are you a success? A failure?
A parent? An athlete? A wallflower?
A Christian? A Buddhist? A baker?
If we are only a collection of stories about ourselves... what's the truth of who "we" are?
Looking for UNCUT...Read more
America is famously a nation of immigrants, a melting pot of cultures. And yet, few subjects will be debated as passionately this year as immigration reform. What are we really talking about, when we argue about immigration? And, what's it like to be 'fresh off the boat" in a country that...Read more
Thirty years ago, the Iranian Revolution rocked the Middle East and upended the country's cozy relationship with America. We'll take stock of Iran three decades later as we examine the country and it's culture through music, film and politics. Also Salman Rushdie reflects back on "The Satanic...Read more
Ira Glass has helped reinvent storytelling on the radio. But he says it took him years to learn how to tell a good radio tale. In this hour of To the Best of Our Knowledge, Ira Glass ont the art of telling stories. We’ll also visit The Moth – the mecca of storytelling in New York City. And...Read more
Some people think they just can’t do math, but it turns out our brains are hard-wired for adding, subtracting, multiplying and dividing. We’re born with a numbers sense. In this hour of To the Best of Our Knowledge celebrating our mathematical minds. Also, the natural history...Read more
A car accident at twenty-one left John Callahan paralyzed. He’s become a very successful cartoonist -- poking fun at disabilities and the idiosyncrasies of life. His work has been described as “rude, shocking, tasteless, and depraved” – by his fans. Next time on To...Read more
It’s Oscar season and Hollywood is once again celebrating the best films of the year. It would seem that we're a nation obsessed with movies. As a country, we spend billions of dollars to watch them every year, and celebrate them with a variety of awards ceremonies. But what separates a...Read more
We run for all sorts of reasons -- to lose 10 pounds, to win an Olympic medal, or simply because it’s fun. Some even run as a spiritual practice. Today, why we run - and how far and how fast can humans go?Read more
For eons Mars has been the toast of the galaxy – and has ignited the human imagination. The Red Planet is home to the God of War – and to little green men. In this hour of To the Best of Our Knowledge, exploring Mars. We’ll get the latest on NASA’s new Mars missions, and take a look at the...Read more
Who says it's only humans who make art? Have you ever seen an elephant paint? Move over Jackson Pollock - elephant masterpieces are heading to the auction block! And when it comes to music well, Renee Fleming's got a nice voice, but have you have heard a whale sing? It's unbelievable. In this...Read more
Sinatra swings it, Miles Davis jazzes it up, and Billy Holiday croons it from the heart. Next time on To the Best of Our Knowledge, the biography of a great American love song. In our second annual Valentine’s Day Show the Rogers and Hart hit “My Funny Valentine.” And our listeners share true...Read more
In Japan’s ancient Edo period, the math geek was born – but it’s not who you think! Samurai, women, children and farmers were among the original creators of the sangaku - Japanese temple geometry. In this hour of To the Best of Our Knowledge, math for the gods. Also, can numbers unlock the...Read more
As Hillary Rodham Clinton prepares to give the most important speech of her life, listen back to the speech that marked her entrance into public political life, now available for the first time in its entirety. On May 31st, 1969, Hillary Rodham became the first student to give a commencement...Read more
Americans change their dining room tables about as often as they change their spouses, about one and a half times in their lives. IKEA isn’t concerned about your marriage, but it does want to change the way you look at your furniture, and yourself. In this hour of To the Best of Our Knowledge...Read more