Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Imagine the world as we know it, only without us. In this hour of To the Best of Our Knowledge, a writer imagines a world reinventing itself without human beings. He sees the New York subway system returning to its watery origins. The re-absorption of carbon into the earth, and endangered...Read more
Charles Monroe-Kane grew up hearing voices in his head. For years he tried to drown them out with potentially lethal quantities of hard drugs and alcohol. Lithium saved his life but coming clean about his past hasn't been easy. How do you admit, as a public radio producer, that for years you had...Read more
Batman, Superman, the Green Lantern we all had our superheroes as kids. Maybe we still do today? In this hour of To the Best of Our Knowledge, SUPERHEROES. We'll celebrate Wonder Woman's 70th birthday with a look at her controversial new costume. We'll also explore the actual physics of...Read more
As the Zika virus continues to make headlines, consensus is slowly growing among scientists that it’s showdown time for the mosquito. Time to marshal the technology to wipe them off the face of the earth. Which seems pretty extreme. Doesn’t it?
So, should we bio-...Read more
He was the most surprising Booker Prize winner in years. DBC Pierre had been a con man and a drug addict before he became a writer. Now he’s won one of the world’s great literary prizes. In this hour of To the Best of Our Knowledge we’ll talk with some award-winning writers including DBC...Read more
Chris Ayres never wanted to cover the war. He was perfectly content reporting on celebrity gossip in L.A. But through a twist of fate, he found himself embedded with Marines in Iraq, living in a Humvee and waiting for his death at the hands of the Republican Guard. In this hour of To the Best...Read more
Gore Vidal has a special fondness for the Founding Fathers, especially George Washington. “The others were geniuses. He was not a genius” he says, but “he had a powerful character which got him through the revolution, since he was not much of a general. But he was a great leader.” We’ll talk...Read more
Physicist Lawrence Krauss says science can finally explain the age-old mystery: How can something come out of nothing? Or, to be more specific, how can the Big Bang pop out of empty space? Krauss also set off an intellectual brawl by saying theologians and philosphers have nothing...Read more
Thousands of the world's languages are disappearing in the wake of globalization. And because language is the DNA of culture, a lost language is a lost culture. Today, stories from the frontlines of the language revitalization movement. Also, Dr. Larry Brilliant's improbable journey from...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
Remember the good old days? No? Well that's either because you haven't lived them yet, or you need to check the note you left on the bedside table. In this hour of To the Best of Our Knowledge, we're looking at age and memory with a Nobel Prize winner searching through the mechanics of the brain...Read more
You know the earth is round, the sky is up, and your dog loves you. But HOW do you know those things? This week, how we form opinions – the psychology and brain chemistry behind our beliefs.Read more
Grim news from Africa is easy to find, but there are good things happening there too. The creator of the Number 1 Ladies’ Detective Agency wants you to know all about them. He calls himself a Utopian writer. In this hour of To the Best of Our Knowledge, we’ll visit the real Botswana with...Read more
Filmmaker Ken Burns calls the national parks "America's best idea." We'll take you to Yosemite,Denali and Carlsbad Caverns. We'll also explore some forgotten parts of our history: how the "buffalo soldiers" helped create America's first parks, and why the very idea of protecting nature has...Read more
In the early 1950's two-year-old Jacqueline Henley in New Orleans became darker. After the neighbors complained, her aunt turned her over to New Orleans authorities. A black couple wanted to adopt Jacqueline but -- she had the word “white” stamped on her birth certificate. Next time on To...Read more
Wouldn't it be great if we could predict the future? We could invest wisely, prepare for social change, and have next season's fashionable footwear.
But in our accelerated world, it seems increasingly difficult to figure out what the next big thing will be. In this hour, are trends a...Read more
The past is nebulous - a place no one can go. When we try to get our bearings there, we often find more than one truth. In this hour of To the Best of Our Knowledge, we’ll go back to Vietnam with Senator Bob Kerrey. And, one woman pieces together her past in war-torn Liberia. Also, paying...Read more
"Everyone is on the Internet but they're not all talking with each other. There are groups upon groups out there, but they don't talk to one another. So while the Internet brings everyone into a share space, it does not necessarily bring them together." -- David LynchRead more
This hour we combine two seemingly unlikely things: food and death. But when you think about it food and death really do go hand-in-hand. From the Last Meal to the new phenomenon of Death Dinners. Read more
Thomas Paine was a working class Englishman without many prospects when he landed in America in 1774. Two years later his pamphlet "Common Sense" laid the foundation for the Declaration of Independence and transformed American politics. In this hour of To the Best of Our Knowledge, why...Read more
Everyone knows what comic books are about, right? But it's not all about people in long underwear hitting each other. This hour on To the Best of Our Knowledge, heroes, anti-heroes, and regular folks strutting their stuff in black and white.Read more