Scientists are launching one of the most audacious projects ever conceived: a detailed map of the human brain, neuron by neron, synapse by synapse. For some scientists...Read more
Intelligent. Optimistic. Curious.
Episode Archives
How do you soak in the essence of a city? In New York, writer Colson Whitehead goes walking ... through Times Square, along Broadway, down into the subway. In Memphis, critic Robert Gordon listens to its music - the blues, soul, rock-n-roll. Next time on To the Best of Our Knowledge, we’ll...Read more
The legendary movie mogul Samuel Goldwyn once said, you should never predict anything, especially the future. But it’s human nature to go to extremes for a sneak peak of what lies around the corner. In this hour of To the Best of Our Knowledge, an astrophysicist sheds some light on...Read more
The American middle class used to be living proof that the American dream was alive and well, providing homes and modest savings to anyone willing to work. It’s another story today. In this hour, the decline of the middle class. How rising levels of income inequality shattered...Read more
Do African-Americans believe Jesse Jackson speaks for them? A resounding 72% between the ages of 18 and 45 say "No." In this hour of To the Best of Our Knowledge, the battle between the Civil Rights generation and the Hip-Hop generation. We'll speak to young blacks about who does speak for them...Read more
Lynne Truss created a sensation in Britain with a book whose title is a punch line: it’s a punctuation joke that says a panda is a black and white mammal and it “Eats, Shoots and Leaves.” Rules for punctuation and a good life, in this hour of To the Best of Our Knowledge.Read more
Plugged into devices, fixated on screens, their world muted by headphones jammed in their ears, college students on campus in Ann Arbor can seem oblivious to risk. Poet Laura Kasischke marvels at their fearlessness in...Read more
American citizens worry about suicide bombers on airplanes, but intelligence analysts say the real threat today is in cyberspace. Cyber attacks on American companies and military installations are on the rise. Could terrorist hackers take down America's power grid? Or financial networks. In...Read more
When Meg Gaines was diagnosed with terminal cancer, her doctor told her to go home and think about the quality, not the quantity, of her days. Instead she grabbed him by the bow-tie and said “I don’t think you understand. I intend to live.” Today Meg Gaines is helping other cancer patients...Read more
What makes a great school? Is it the quality of teaching, class size, or the curriculum? When it comes to school reform, everyone seems to have an opinion. Today, we're rethinking schools and the way we teach.Read more
Linus has his security blanket. Renowned neurologist Oliver Sacks had the Periodic Table of the Elements. In this hour of To the Best of Our Knowledge, My Chemical Life. Oliver Sacks remembers a childhood steeped in chemistry. Also, Primo Levi survives Auschwitz, through chemistry. And,...Read more
According to a "New York Times" poll he's the third most famous person in Japan, right behind Hirohito and Bruce Lee. But the truth is he's not even a person, he's a giant green, radioactive lizard named Godzilla. In this hour of To the Best of Our Knowledge we'll explore the history of...Read more
Do you have a tattoo? One in five American adults do. It seems there are tattoo parlors everywhere. What’s most popular? Quotes from great works of literature. "So it goes."Read more
You know who they are – the cool kids – those above-it-all taste-makers whose fashion and entertainment choices predict what everyone else will be wearing and doing next year. What’s their secret? In this hour of To the Best of Our Knowledge exploring cool. A frustrated surfer remembers...Read more
A car accident at twenty-one left John Callahan paralyzed. He’s become a very successful cartoonist -- poking fun at disabilities and the idiosyncrasies of life. His work has been described as “rude, shocking, tasteless, and depraved” – by his fans. Next time on To...Read more
Can you imagine spending a week at an airport? By choice? Alain de Botton did exactly that. He tells us about it, as we explore airports and air travel.Read more
The thrill of victory… the agony of defeat. And the human drama of athletic competition. We love sports. And every 4 years we get the pleasure to watch amateur athletes, at the top of their game, compete in the Olympics. And that got us thinking about competition. Because that’s what it’s...Read more
It’s Oscar season and Hollywood is once again celebrating the best films of the year. It would seem that we're a nation obsessed with movies. As a country, we spend billions of dollars to watch them every year, and celebrate them with a variety of awards ceremonies. But what separates a...Read more
We run for all sorts of reasons -- to lose 10 pounds, to win an Olympic medal, or simply because it’s fun. Some even run as a spiritual practice. Today, why we run - and how far and how fast can humans go?Read more
For eons Mars has been the toast of the galaxy – and has ignited the human imagination. The Red Planet is home to the God of War – and to little green men. In this hour of To the Best of Our Knowledge, exploring Mars. We’ll get the latest on NASA’s new Mars missions, and take a look at the...Read more
Here’s the bad news. You can get the thing you most want - a BMW, the winning lottery ticket, and you still won’t be any happier. The good news? You can survive the most devastating catastrophes and you’ll be back on your feet in less time than you think. Next time on To the Best of Our...Read more
Adventure writer Ann Jones recalls crossing Africa from Tangier to Cape Town in search of one special tribe. They’re guided by the “feminine” principles of compromise, tolerance and peace. Also, Tony Horwitz sets sail in the wake of Captain Cooke. We’ll hear about a Frenchman who never went...Read more
Homer called salt a divine substance. Salt taxes built empires across Europe and Asia. They even sparked a revolution. In this hour of To the Best of Our Knowledge, why salt is no ordinary rock. We’ll tell you how it’s changed the course of history. Also, the...Read more
Andre Agassi says he always hated tennis, even though it's what made him rich and famous. But maybe that's not surprising, considering how his father used to browbeat him into hitting 2500 balls a day when he was seven years old, and later sent him off to a tennis academy, which Agassi calls a "...Read more