In the first episode in our series about psychedelics, how can psilocybin ease our fears about dying and help us make peace with the end of our lives?More
Are you ready for the psychedelic revolution? In the next few years, the FDA is likely to approve these mind-bending drugs for treating depression and post-traumatic stress disorder. Some states have already decriminalized psilocybin, the active ingredient in "magic" mushrooms. But for all the headlines, many questions are swirling around this psychedelic renaissance. How do we make these drugs effective, safe and accessible to the people who need the most help? And how can they be used ethically, when much of the knowledge about plant medicines comes from Indigenous cultures? Psychedelics also raise profound questions about the nature of consciousness and mystical experience. People often describe their psychedelic experiences as “more real” than everyday life. Is this just an illusion, or do these experiences tap into some deeper reality?
In “Luminous,” TTBOOK executive producer Steve Paulson explores the philosophical and cultural implications of psychedelics through conversations with scientists, healers and religious scholars. You can listen to each episode on the radio or find the series plus bonus extended conversations on Apple Podcasts, Spotify, YouTube or wherever you get your podcasts.
Bill Linton is on a mission. He wants to get FDA approval for using psychedelics to treat depression and addiction. So he co-founded his own nonprofit psychedelic center, Usona Institute, to help revolutionize the treatment of mental illness.More
A decade ago, Lou Lukas took part in one of the first trials of psilocybin-assisted therapy. Today, she's a palliative medicine physician and an advocate for psychedelic-assisted therapy – especially for people living in fear near the end of life.More
Tony Bossis was one of the lead investigators on the 2016 study that found stress reduction in cancer patients after a single dose of psilocybin. He's fascinated by how the mystical experiences of the great religions map onto psychedelic experiences.More
Roland Griffiths helped pioneer the use of psychedelics to treat people with cancer who are scared of dying. Then he got his own terminal diagnosis. He talks with Steve Paulson about his personal LSD journey when he "talked" with his cancer.More
A psychedelic research center in Wisconsin is gearing up to manufacture enough medical-grade psilocybin to supply the world. Steve Paulson went to Usona Insitute to see where the magic's made, and got a peek inside the lab of chemist Alex Sherwood.More
”To the Best of Our Knowledge” is a Peabody award-winning national public radio show that explores big ideas and beautiful questions. Deep interviews with philosophers, writers, artists, scientists, historians, and others help listeners find new sources of meaning, purpose, and wonder in daily life. Whether it’s about bees, poetry, skin, or psychedelics, every episode is an intimate, sound-rich journey into open-minded, open-hearted conversations. Warm and engaging, TTBOOK helps listeners feel less alone and more connected – to our common humanity and to the world we share. Learn more about the show here.
Roland Griffiths is a neuroscientist at Johns Hopkins. He's just turned his attention to psilocybin, a classic hallucinogen commonly known as magic mushrooms. He tells Steve Paulson about his findings.More
June 05, 2011
Magic mushrooms go way back in human history. Some people even believe psychedelic mushrooms helped create human consciousness. We examine the "Stoned Ape Theory."More
June 06, 2019
Can psychedelics help you find God? Clinical psychologist Bill Richards thinks so. More
March 05, 2017
After the excesses of the 1960s — and an ensuing moral panic — psychedelic research was outlawed by the United States government for decades. But today, the research is blossoming as a promising treatment for depression and anxiety.More
February 15, 2020
How taking microdoses of LSD for a month helped her find a calm she hadn’t known for years.More
March 05, 2017
Desperate for help with his PTSD, Dan Kasza took a strange brew of frog venom and ayahuasca.More
March 05, 2017