Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
TTBOOK staffers share some of our favorite interviews and shows produced by our favorite Canadian. Read more
Salman Rushdie's new novel is called "The Enchantress of Florence." It's a tale of two cities, consisting of stories tucked inside stories tucked inside stories...along the lines of Scheherazade's stories of "One Thousand and One Nights." In this hour of To the Best of Our Knowledge, Salman...Read more
In this hour of To the Best of Our Knowledge, Russia and China. They were the two Communist giants. Now each is carving out a new future. By most accounts, China is doing it better. It’s still an authoritarian state, but the economy if booming. And Russia? Well, it’s capitalism’s wild...Read more
Read any good life-list books lately? How about "1,000 Places You Must Visit Before You Die?" or "1,001 Movies You Must See Before You Die." There's no shortage of "life-list" books to read these days. What's next? "1,000 Life-List Books You Must Read Before You Die"? Probably. We'll explore...Read more
Think that a TV series based on the Coen Brothers' 1996 black comedy crime thriller, "Fargo," is a bad idea? Then you haven't seen "Fargo," The TV series. Creator and showrunner Noah Hawley talks about how he transformed the iconic film into the critically-acclaimed, award-winning TV series.Read more
Chris Ayres never wanted to cover the war. He was perfectly content reporting on celebrity gossip in L.A. But through a twist of fate, he found himself embedded with Marines in Iraq, living in a Humvee and waiting for his death at the hands of the Republican Guard. In this hour of To the Best...Read more
Who's calling your shots? Who's in charge of your thinking, your perceptions? Maybe it's simple. Your mind is the boss, then your brain runs your body. Everything's fine. Until it's not and you find yourself confronting depression or autism or a head injury that leaves you with brain damage....Read more
Everyone knows what comic books are about, right? But it's not all about people in long underwear hitting each other. This hour on To the Best of Our Knowledge, heroes, anti-heroes, and regular folks strutting their stuff in black and white.Read more
Of all the days in the life of Nelson Mandela - the days in jail, awaiting sentence and his election in 94 - one day stood out as the most nerve-wracking. The day of the Rugby World Cup in 1995 - South Africa versus New Zealand. But it was much more than a sports match. It was the chance to...Read more
Seven hundred million people get their music from the Internet. More than 10 million people own iPods. Does this mean that compact discs and record companies are going the way of the gramophone and eight-track tapes? In this hour of To the Best of Our Knowledge, we'll look at this digital...Read more
Reading a good book may be the most fun you can have sitting down. Books can be a hobby or a passion, an interest or an obsession. In this hour of To the Best of Our Knowledge, tales from book world. A former bookseller takes us to Hay on Wye - the Welsh town that’s well on its way to...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
Want to learn a second or third language? You don’t have to slave away in a French seminar – it only takes a minute or two to pick up “ob.” Next time on tob-oo thob-ah bob-est ob-of ob-our knob-ow-lob-edge. Or should I say To the Best of Our Knowledge, word games, and secret...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
In the wake of a number of high profile shootings over the past year, people are talking about policing, racism, and injustice. But there's one issue we don't really talk all that much about: fear.This hour, we take a closer look at negative stereotypes about African American men, how those...Read more
"Shhh… I have a secret… Now, I could tell you but then I'd have to kill you." Classic spy joke – but not so funny when it's true. In this hour of To The Best of Our Knowledge, we'll go the dark side of secrecy - warrantless wiretapping, secret CIA prisons, "extraordinary rendition,"...Read more
Violence may be a national scourge, but an awful lot of people devour shoot-‘em-up movies and video games. In this hour of To the Best of Our Knowledge, the seduction of violence. Why, for instance, four and five-year-old children love fantasy games where they kill each other. Also, the...Read more
Modern medicine can treat disease at a molecular—or even atomic – level. And today’s surgeons can fix things the naked eye can’t even see. But there’s one thing every patient wants that no technology in the world can provide: compassion. In this hour, doctors talk about the...Read more
One of the biggest challenges a journalist can face is reporting a story when your connection to your source is compromised. They won't talk, or they can't talk, or it's your own father. Can anyone ever uncover the truth, the whole truth, about another person?Read more
Your name is a collection of sounds and syllables that identify you. It's your tag, handle, label, second skin. It's written on your birth certificate and it'll be inscribed on your grave. But what does it actually mean? Names carry family dreams, expectations and legacies....Read more
Bohemians used to hate anything that reeked of money. It destroyed the soul. Now, many self-styled bohemians are reveling in slate shower stalls, Range Rovers, and lava-rock grills. In this hour of To the Best of Our Knowledge, the triumphs of the “Bobo” – the Bourgeois...Read more
Failure is a four letter word in America. Most of us do everything we can to avoid it. But what if we've got the wrong idea about failure - and it's all a matter of learning the right way to do it? This hour, one psychologist's take on how to embrace the fall. And comedian...Read more