Turns out there is an emerging science of uncertainty — a new frontier in psychology, artificial intelligence, and surgery — where things can go very wrong when people are missing a crucial skill set: being unsure. Maggie Jackson explains.

There are two sides to giving up. The virtue of sacrifice – and the sin of despair. So how do we decide which is which? That’s the question psychoanalyst Adam Phillips asks in his newest book “On Giving Up.”